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Literature summary extracted from

  • Colonna, S.; Pironti, V.; Pasta, P.; Zambianchi, F.
    Oxidation of amines catalyzed by cyclohexanone monooxygenase (2003), Tetrahedron Lett., 44, 869-871.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.13.22 expressed in Escherichia coli Acinetobacter calcoaceticus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.13.22 60000
-
-
 Acinetobacter calcoaceticus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.22 cyclohexanone + NADPH + O2 Acinetobacter calcoaceticus
-
 hexano-6-lactone + NADP+ + H2O
-
 ?
1.14.13.22 cyclohexanone + NADPH + O2 Acinetobacter calcoaceticus NCIMB 9871
-
 hexano-6-lactone + NADP+ + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.22 Acinetobacter calcoaceticus
-
 NCIMB 9871
-
1.14.13.22 Acinetobacter calcoaceticus NCIMB 9871
-
 NCIMB 9871
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.13.22 recombinant protein from Escherichia coli Acinetobacter calcoaceticus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.22 cyclohexanone + NADPH + O2
-
 Acinetobacter calcoaceticus hexano-6-lactone + NADP+ + H2O
-
 ?
1.14.13.22 cyclohexanone + NADPH + O2
-
 Acinetobacter calcoaceticus NCIMB 9871 hexano-6-lactone + NADP+ + H2O
-
 ?
1.14.13.22 additional information can catalyze the asymmetric sulfoxidation of numerous alkyl aryl sulfides, dialkyl sulfides, 1,3-dithioacetals, organic cyclic sulfites, and the oxidation alkyl aryl amines Acinetobacter calcoaceticus ?
-
 ?
1.14.13.22 additional information can catalyze the asymmetric sulfoxidation of numerous alkyl aryl sulfides, dialkyl sulfides, 1,3-dithioacetals, organic cyclic sulfites, and the oxidation alkyl aryl amines Acinetobacter calcoaceticus NCIMB 9871 ?
-
 ?
1.14.13.22 N-methylbenzylamine + NADPH + O2
-
 Acinetobacter calcoaceticus N-benzyl-N-methylhydroxylamine + NADP+ + H2O
-
 ?
1.14.13.22 N-methylbenzylamine + NADPH + O2
-
 Acinetobacter calcoaceticus NCIMB 9871 N-benzyl-N-methylhydroxylamine + NADP+ + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.13.22 monomer 1 * 60000 Acinetobacter calcoaceticus

Synonyms

EC Number Synonyms Comment Organism
1.14.13.22 cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming)
-
 Acinetobacter calcoaceticus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.22 FAD one FAD bound per enzyme molecule Acinetobacter calcoaceticus
1.14.13.22 NADPH
-
 Acinetobacter calcoaceticus